September 14, 2020
U.S. Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549
| Attention: | Eric Atallah |
| Al Pavot |
| Laura Crotty |
| Jeffrey Gabor |
| Re: | Dyne Therapeutics, Inc. |
Registration Statement on Form S-1 (File No. 333-248414)
Request for Acceleration
Ladies and Gentlemen:
Pursuant to Rule 460 of the General Rules and Regulations under the Securities Act of 1933, as amended, we wish to advise that as of the date hereof, approximately 4,605 copies of the Preliminary Prospectus dated September 10, 2020 were distributed to prospective underwriters, institutional investors and prospective dealers in connection with the above-captioned Registration Statement.
We wish to advise you that the participating underwriters have informed us that they have complied and will continue to comply with the requirements of Rule 15c2-8 under the Securities Exchange Act of 1934, as amended.
We hereby join in the request of the registrant that the effectiveness of the above-captioned Registration Statement, as amended, be accelerated to 4:00 p.m. Eastern Time, on September 16, 2020 or as soon thereafter as practicable.
[Signature page follows]
| Very truly yours,
J.P. MORGAN SECURITIES LLC JEFFERIES LLC PIPER SANDLER & CO. STIFEL, NICOLAUS & COMPANY, INCORPORATED
As representatives of the Underwriters J.P. MORGAN SECURITIES LLC | ||
| By: | /s/ David Ke | |
| Name: David Ke Title: Executive Director | ||
| JEFFERIES LLC | ||
| By: | /s/ Dustin Tyner | |
| Name: Dustin Tyner Title: Managing Director | ||
| PIPER SANDLER & CO. | ||
| By: | /s/ Chad Huber | |
| Name: Chad Huber Title: Managing Director | ||
| STIFEL, NICOLAUS & COMPANY, INCORPORATED | ||
| By: | /s/ Nicholas Oust | |
| Name: Nicholas Oust Title: Managing Director | ||
[Signature Page to Dyne Therapeutics, Inc. Acceleration Request]